ABSTRACT
OBJECTIVE@#To improve the method of vermillion flap and orbicularis oris bundle anastomosis in repair of transverse facial cleft.@*METHODS@#Based on the precise fixed point, the modified vermillion flap was designed slender at the new corner of the upper lip, and was inserted into the lower lip after removing part tissue. The orbicularis oris was divided into two bands and cross-stitched.@*RESULTS@#Fifteen patients with unilateral transverse facial cleft form the Children's Hospital of Zhejiang University during September 2016 and December 2018 were operated, and the position and shape of the commissure were almost normal.@*CONCLUSIONS@#The cosmetic effect and oral function are satisfactory when the modified vermillion flap and bundle anastomosis of orbicularis oris is used to repair transverse facial cleft.
Subject(s)
Child , Humans , Anastomosis, Surgical , Cleft Lip , General Surgery , Facial Muscles , General Surgery , Lip , General Surgery , Surgical Flaps , General Surgery , Treatment OutcomeABSTRACT
Chronic diseases (ChDs) today constitute the leading cause of morbidity and mortality. Increasing evidence suggests that the production and development of ChDs are associated with amplified inflammation, which is caused by accumulation of advanced glycation end products (AGEs) and advanced lipexidation end products (ALEs).Heating, irradiation, and ionization, in combination with gross over-nutrition, significantly contribute to production of, exposure to and accumulation in the body of AGEs/ALEs. Furthermore, dietary AGEs restriction in animals seemed to be effective to extend life span. This paper elucidates the relationship between food and AGEs and the dietary measures to reduce AGEs/ALEs with an attempt to provide new methods for prevention and treatment of ChDs.